Combined Immunodeficiency Disease and Adenosine Deaminase Deficiency. A Molecular Defect

mice are discussed by Alfred S. Steinberg who presents data in support of the idea that early loss of a thymic regulatory function in these mice may account for a breakdown in tolerance to "self" and certain other antigens, leading to excessive antibody responses with immune complex formation. The last two chapters, one by Stanley A. Plotkin, the other by Frautisek Sokol, deal, respectively, with the pros and cons of killed and live vaccines. I can recommend this book as an appetizer. It certainly whets one's appetite, but is insufficient as a meal in itself.